Subcorneal pustular dermatosis associated with rheumatoid arthritis and raised IgA: simultaneous remission of skin and joint involvements with dapsone treatment.
نویسندگان
چکیده
A 44 year old white woman with rheumatoid arthritis for 19 years developed subcorneal pustular dermatosis. She had increased polyclonal IgA and IgA rheumatoid factor. After 4 months' treatment with dapsone 100 mg daily the patient had neither skin lesions nor active joint disease.
منابع مشابه
IgA Pemphigus: Subcorneal Pustular Dermatosis Type - A case report with vesicle and pustular eruption for 13 years cured with dapsone in 3 weeks
IgA pemphigus is a newly characterized group of autoimmune intraepidermal blistering diseases presenting as vesiculopustular eruptions with a predilection in axillary and groin areas. Immunopathologically, IgA deposition in the intercellular space of the epidermis is present in all cases of IgA pemphigus by direct immunofluorescence. However, unlike pemphigus vulgaris, IgA pemphigus carries a r...
متن کامل[subcorneal Pustular Dermatosis. (sneddon-wilkinson Disease)].
Subcorneal pustular dermatosis is a disease that has coalescent, flaccid, recurrent pustules. We do not know everything about its etiology or pathogenesis; however, its autoimmune mechanism links it with neoplastic or immunologic diseases. First line treatment is dapsone. We describe the case of a classic subcorneal pustular dermatosis in a patient in who we could not use dapsone (sulpha drugs ...
متن کاملSubcorneal pustular dermatosis in the pediatric age*
Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs...
متن کاملSubcorneal pustular dermatosis and mycoplasma pneumoniae respiratory infection.
Sir, Subcorneal pustular dermatosis (SPD) is an uncommon, chronic/recurrent, pustular eruption characterized by subcorneal sterile pustules involving mainly the abdomen and the large folds. Originally described in 1956 by Sneddon & Wilkinson (1), the condition can be ascribed to the complex group of neutrophilic dermatoses (2). The pathophysiology underlying SPD is presently unknown, but the di...
متن کاملSubcorneal pustular dermatosis.
Subcorneal dermatosis is a chronic relapsing pustular eruption which has been recognised for 20 years. The diagnosis can be made only by combining the clinical features of a recurrent eruption mainly on the trunk which spares the mucosae and has the histological appearance of a subcorneal bullae filled with polymorphonuclear leucocytes situated on the surface of normal epidermis. No immunofluor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 49 3 شماره
صفحات -
تاریخ انتشار 1990